Bromfenac capsules

What are bromfenac capsules?

BROMFENAC (Duract™) was a nonsteroidal antiinflammatory drug (NSAID). Bromfenac reduced inflammation and treated mild to moderate pain.

NOTE: This drug is discontinued in the United States.

What should my health care professional know before I take bromfenac?

They need to know if you have any of these conditions:

• an alcohol problem

• asthma

• bleeding problems

• cigarette smoker

• coronary artery bypass graft (CABG) surgery within the past 2 weeks

• dental disease

• diabetes

• heart or circulation problems

• kidney disease

• liver disease

• nasal polyps

• stomach or duodenal ulcers

• systemic lupus erythematosus

• ulcerative colitis

• an unusual or allergic reaction to aspirin, other salicylates, other NSAIDs, other medicines, foods, dyes or preservatives

• pregnant or trying to get pregnant

• breast-feeding

How should I take this medicine?

Take bromfenac sodium capsules by mouth. Follow the directions on the prescription label. Swallow the capsules whole with a full glass of water. If bromfenac is taken with foods high in fat, you may need a higher dose. Contact your physician if you plan take bromfenac with foods high in fat. Take your doses at regular intervals. Do not take your medicine more often than directed.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What drug(s) may interact with bromfenac?

• alcohol

• agents that dissolve blood clots

• antiinflammatory drugs (NSAIDs, such as ibuprofen)

• aspirin and aspirin-like medicines

• blood thinners

• cyclosporine

• entecavir

• hormones, such as prednisone or cortisone

• lithium

• methotrexate

• pemetrexed

• water pills

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What should I watch for while taking bromfenac?

Let your prescriber or health care professional know if your pain continues, do not take with other pain-killers without advice. If you get flu-like symptoms (fever, chills, muscle aches and pains), call your prescriber or health care professional; do not treat yourself.

To reduce unpleasant effects on your throat and stomach, take bromfenac with a full glass of water and never just before lying down.

You may get dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how bromfenac affects you. Do not sit or stand up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.

Do not smoke cigarettes or drink alcohol; these increase irritation to your stomach and can make it more susceptible to damage from bromfenac.

If you get black, tarry stools or vomit up what looks like coffee grounds, call your prescriber or health care professional at once. You may have a bleeding ulcer.

What side effects may I notice from taking bromfenac?

Elderly patients are more likely to get side effects.

Side effects that you should report to your prescriber or health care professional as soon as possible:

• black, tarry stools

• decrease in the amount of urine passed

• difficulty breathing

• flu-like symptoms

• skin rash, redness, blistering, peeling or itching

• stomach pain or cramps

• swelling of eyelids, throat, lips or feet

• unusual bleeding or bruising, red spots on the skin

• vomiting

• weight change

• yellowing of eyes or skin

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

• constipation or diarrhea

• dizziness

• gas or heartburn

• headache

• nausea

Where can I keep my medicine?

Keep out of the reach of children in a container that small children cannot open.

Store at room temperature below 30 degrees C (86 degrees F). Protect from moisture. Keep container tightly closed. Throw away any unused medicine after the expiration date.

Bromfenac eye solution

What is Bromfenac eye solution?

BROMFENAC (Xibrom™) eye solution is a nonsteroidal anti-inflammatory drug (NSAID). Bromfenac eye solution helps relieve eye inflammation after eye surgery. Generic bromfenac eye solution is not yet available.

What should my health care professional know before I receive Bromfenac?

They need to know if you have any of these conditions:

• asthma

• bleeding problems

• contact lenses

• diabetes mellitus

• dry eye syndrome, other eye problems, or recent eye surgery

• an unusual or allergic reaction to bromfenac, aspirin, other salicylates, sulfites, other medicines, foods, dyes or preservatives

• pregnant or trying to get pregnant

• breast-feeding

How should this medicine be used?

Bromfenac eye solution is only for use in the eye. Do not take by mouth. Follow the directions on the prescription label. Remove contact lenses before use. Wash hands before and after use. Tilt your head back slightly and pull your lower eyelid down with your index finger to form a pouch. Try not to touch the tip of the dropper to your eye, fingertips, or any other surface. Squeeze the prescribed number of drops into the pouch. Close the eye gently to spread the drops. Your vision may blur for a few minutes. Use your doses at regular intervals. Do not use your medicine more often than directed. Do not use any other eye products without telling your prescriber or health care professional.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a dose?

If you miss a dose, use it as soon as you can. If it is almost time for your next dose, use only that dose. Do not use double or extra doses.

What drug(s) may interact with Bromfenac?

• agents that treat or prevent blood clots such as warfarin or other 'blood thinners'

• agents that affect platelets

• corticosteroids applied to the eye

• latanoprost

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What should I watch for while taking Bromfenac?

Let your prescriber or health care professional know if your eye symptoms do not improve after 2 to 3 days. Do not use for longer than prescribed by your doctor.

Unless your prescriber or health care professional gives you other instructions, you should not wear contact lenses while you are using bromfenac eye drops.

What side effects may I notice from receiving Bromfenac?

Side effects that you should report to your prescriber or health care professional as soon as possible:

• bleeding in the white part of your eye

• skin rash

• sores in the eye or eye irritation that gets worse

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):

• burning or stinging after instilling the drops

• dry, red, or itchy eyes

Where can I keep my medicine?

Keep out of the reach of children in a container that small children cannot open.

Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F). Throw away any unused medicine after the expiration date on the label.